WWOX, the FRA16D gene: A target of and a contributor to genomic instability
T Hussain, B Liu, MS Shrock… - Genes …, 2019 - Wiley Online Library
… and stomach cancers, among other malignancies suggesting its function as a tumor suppressor
… linked to cancer-related chromosomal translocations due to the apparent proximity of …
… linked to cancer-related chromosomal translocations due to the apparent proximity of …
[HTML][HTML] Relative telomere length change in colorectal carcinoma and its association with tumor characteristics, gene expression and microsatellite instability
… and selected group of cancer related genes: In light of well-… shortening was more noticeable
in low-grade tumors (which … /F-statistics for the model error) representing the significance of …
in low-grade tumors (which … /F-statistics for the model error) representing the significance of …
[HTML][HTML] Repetitive DNA sequence detection and its role in the human genome
… Furthermore, HERVs and mammalian apparent LTR … effects on nearby genes, including
cancer-related genes 106 (… These unstable repeats are found in up to 20% of eukaryotic genes …
cancer-related genes 106 (… These unstable repeats are found in up to 20% of eukaryotic genes …
[HTML][HTML] Application of G-quadruplex targets in gastrointestinal cancers: Advancements, challenges and prospects
ZQ Han, LN Wen - World Journal of Gastrointestinal Oncology, 2023 - ncbi.nlm.nih.gov
… , G-quadruplex structures have obvious polymorphisms. X-ray … -quadruplex stability may
reduce replication initiation activity … G-quadruplexes of cancer-related genes in cancer cells and …
reduce replication initiation activity … G-quadruplexes of cancer-related genes in cancer cells and …
DNA methylation profiling of hTERT gene alongside with the telomere performance in gastric adenocarcinoma
S Vahidi, SE Norollahi, S Agah… - Journal of Gastrointestinal …, 2020 - Springer
… impress the gene expression and genomic stability and cause … and miRNA via silencing
cancer-related genes or the control … It is now significantly obvious that TERRA transcripts actively …
cancer-related genes or the control … It is now significantly obvious that TERRA transcripts actively …
[HTML][HTML] Unboxing the molecular modalities of mutagens in cancer
… devoted to protect the DNA to ensure genetic stability, any … radiations, DNA replicative errors,
and various endogenous and … Evident studies suggest that ubiquitin E3 ligases such as the …
and various endogenous and … Evident studies suggest that ubiquitin E3 ligases such as the …
[HTML][HTML] Automated next-generation profiling of genomic alterations in human cancers
… for examination of 505 cancer-related genes. Independent … tissue complete microsatellite
instability detection approach … To evaluate the limit of blank, or the apparent TMB in samples …
instability detection approach … To evaluate the limit of blank, or the apparent TMB in samples …
[HTML][HTML] BAP1 as a guardian of genome stability: implications in human cancer
… in human cancers and the roles of BAP1 in many cancer-related … The BAP1 phosphorylation
mutant exhibited no apparent … of chromothripsis are replication stress and mitotic errors, the …
mutant exhibited no apparent … of chromothripsis are replication stress and mitotic errors, the …
N4‐Acetylcytidine Drives Glycolysis Addiction in Gastric Cancer via NAT10/SEPT9/HIF‐1α Positive Feedback Loop
Q Yang, X Lei, J He, Y Peng, Y Zhang, R Ling… - Advanced …, 2023 - Wiley Online Library
… fourth major cause of cancer-related deaths worldwide in 2020… To identify the key ac4C sites
that regulate mRNA stability, … cells in hypoxia had obvious mitochondrial dysfunction, with a …
that regulate mRNA stability, … cells in hypoxia had obvious mitochondrial dysfunction, with a …
[HTML][HTML] Aberrant HMGA2 Expression Sustains Genome Instability That Promotes Metastasis and Therapeutic Resistance in Colorectal Cancer
R Campos Gudino, KJ McManus, S Hombach-Klonisch - Cancers, 2023 - mdpi.com
… of aberrations in cancer-related genes provides subpopulations … CIN; for example, segregation
errors are typically associated with … This HMGA2 protective effect is particularly evident at …
errors are typically associated with … This HMGA2 protective effect is particularly evident at …